Isotonix - the World's Most Advanced Nutraceuticals
Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.

Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.

Methylcobalamin (Vitamin B12): 120 mcg
Vitamin B12 (cobalamin) is a bacterial product naturally found in animal products, especially organ meats such as liver, with small amounts derived from peanuts and fermented soy products, such as miso and tempeh. It is essential that vegetarians consume a vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. It supports the maintenance of cells, especially those of the nervous system, bone marrow and intestinal tract. Vitamin B12 is important in homocysteine metabolism (homocysteine is an amino acid that is formed within the body). Normal homocysteine levels are important for maintaining cardiovascular health.  Deficiencies of the vitamins folic acid, pyridoxine (B6), or cobalamin (B12) can result in elevated levels of homocysteine). Folate and B12, in their active coenzyme form, are both necessary cofactors for the conversion of homocysteine to methionine, thus helping to maintain healthy blood levels of homocysteine.*

Methylcobalamin is one of the naturally occurring forms of vitamin B12 found in the human body. The liver must convert cyanocobalamin, the form of B12 most commonly used in supplements, into methylcobalamin before it can be properly utilized by the body; methylcobalamin is more effective than non-active forms of vitamin B12.  Methylcobalamin also assists in the formation of SAMe (S-adenosylmethionine), a nutrient that has powerful mood-elevating properties.* 

 
Folic Acid (Calcium Folinate): 800 mcg
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans, peas and Brewer’s yeast are the best sources.  Folic acid plays a key role in boosting the benefits of B12 supplementation. These two B vitamins join forces and work together in maintaining normal red blood cells. Folic acid assists in the normal utilization of amino acids and proteins, as well as supporting the construction of the material for DNA and RNA synthesis, which is necessary for all bodily functions. Scientific studies have found that when working in tandem with folic acid, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system.*

 
Folic acid (folate) must go through a series of chemical conversions before it becomes metabolically active to be properly utilized. Folinic acid is the highly bioavailable, metabolically active derivative of folic acid. It does not require the action of the enzyme dihydrofolinate reductase to become active, so it’s not affected by medicines and herbs that inhibit this enzyme. Inhibition of this enzyme can result in folic acid deficiency. Some people have a genetic variation (in the MTHRF gene) that reduces the amount of activated folic acid in the body. Folinic acid, unlike folic acid, is not negatively impacted by this genetic variation.*

Riboflavin-5-Phosphate (Vitamin B2): 3 mg
Vitamin B2 is found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a coenzyme, working with other B vitamins. It promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth. It supports healthy skin, nails, hair growth and helps regulate thyroid activity (a healthy thyroid is essential in maintaining a healthy weight, among other things). Vitamin B2 plays a crucial role in turning food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women, as well as athletes due to their higher caloric needs. Vitamin B2 also aids in the breakdown of fats. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.*

Pyridoxal-5-Phosphate (Vitamin B6): 6 mg
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. B6 is a co-factor required for protein and amino acid metabolism and helps maintain proper fluid balance. It also assists in the maintenance of healthy red and white blood cells which keeps our body healthy. Vitamin B6 is required for hemoglobin synthesis (hemoglobin is the protein portion of red blood cells which carries oxygen throughout the body). Because vitamin B6 is involved in the synthesis of neurotransmitters in the brain and nerve cells, it has been recommended as a nutrient to enhance mental function, specifically mood. Athletic supplements often include vitamin B6 because it promotes the conversion of glycogen to glucose for energy in muscle tissue. Vitamin B6, when taken with folic acid, has been shown to help maintain normal plasma levels of homocysteine, which promotes optimal cardiovascular health. Vitamin B6 should be administered as a part of a complex of other B-vitamins for best results.*

Magnesium (Carbonate): 40 mg  
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green, leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, milk, refined and processed foods contain low amounts of magnesium. Recent research shows that many American diets are magnesium deficient.*

Magnesium is a component of the mineralized part of bone and promotes the normal metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenalin and insulin. It also supports the transportation of calcium inside the cell for utilization. Magnesium plays a key role in the functioning of muscle and nervous tissue, and the synthesis of all proteins, nucleic acids, nucleotides, fats and carbohydrates. Magnesium helps slow the aging process by combating oxidative stress.*

Magnesium is required for releasing energy from food during metabolism, regulation of body temperature, proper nerve function and helping the body handle stress. Importantly, magnesium also promotes is also required by the body to build healthy bones, teeth and normal muscle development. It works together with calcium and vitamin D to help keep bones strong. Magnesium, when combined with calcium, helps support the heart muscle in maintaining a regular heartbeat and promoting normal blood pressure.* 

Potassium (Bicarbonate): 94 mg
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, potassium promotes the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids and the maintenance of normal blood pressure.*

In 1928, it was first suggested that high potassium intake could help maintain cardiovascular health. Potassium promotes normal muscle relaxation and insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes normal heartbeat. Potassium is important in releasing energy from protein, fat and carbohydrates during metabolism. Potassium helps regulate water balance, aids in recovery from exercise and helps with the elimination of wastes. Sodium and potassium are two of the most important ions in maintaining the homeostatic equilibrium of the body fluids.*

Thiamin HCl (Vitamin B1): 2 mg
Thiamin promotes normal carbohydrate metabolism and nerve function.  Thiamin is required for a healthy nervous system, and supports the production of certain neurotransmitters which have an important role in muscle function. It supports the digestive process, increases energy and helps promote mental clarity.*

D-Calcium Pantothenate (Vitamin B5): 20 mg
Pantothenic acid (B5) promotes proper neurotransmitter activity in the brain. Pantothenic acid is also known as the anti-stress vitamin because it detoxifies brain tissue, helps relieve physical and emotional stress, and promotes the secretion of hormones essential for optimal health.*

Niacinamide (Vitamin B3): 20 mg
Niacin is a water-soluble vitamin necessary for many aspects of health, growth and reproduction. Niacin supports the proper functioning of the digestive system, skin and nerves. It is also important for the conversion of food to energy. Niacin is found in dairy products, poultry, fish, lean meats, nuts, eggs, legumes, and enriched breads and cereals.*

Biotin (Vitamin B7): 300 mcg
Biotin can be found in food sources such as egg yolks, peanuts, beef liver, milk, cereals, almonds and Brewer’s yeast. Biotin promotes healthy cell growth, the production of fatty acids, metabolism of fats and amino acids. It supports the citric acid cycle, which is the process in which energy is generated during exercise. Biotin is also helpful in maintaining steady blood sugar levels. Biotin is often recommended for strengthening hair and nails.*

These 10 ingredients combined with the superior delivery of Isotonix® create a powerhouse B vitamin product superior to the rest on the market. Isotonix Activated B-Complex delivers all of the B vitamins along with select minerals and electrolytes to help boost energy, decrease stress, improve mood, and much more. The activated forms of select vitamins and ensure maximal utilization by the body for optimal results.*

What does "Activated” refer to in Isotonix Activated B-Complex?
Activated refers to the active forms of vitamins B6, B12 and folic acid. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, there are circumstances in which this reaction is either slowed or inhibited.

What is the source of the vitamin B12 in our Isotonix Activated B-Complex?
Vitamin B-12 comes from bacteria. B12 in our diet can come from eggs or meats, or by taking a supplement. Vegetarians are recommended to take a B vitamin dietary supplement due to their lack of meat intake.

Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases and reduced levels of these vitamins have been associated with impaired cognitive performance, including vitamin B12. B12 plays a critical role in promoting normal energy production and nervous system function.*

Is it toxic to take too much vitamin B12?
Vitamin B12 has not demonstrated any form of toxicity. As always, we only recommend the product to be taken as directed in the instructions.

Are there any warnings or contraindications for Isotonix Activated B-Complex?
If you are currently taking any prescription drug, have ongoing medical condition, or are pregnant or breastfeeding, you should consult your healthcare provider before using this product. There are no allergens associated with this product.